Neural stem cells have potential of producing variety of neural cell types And useful to cure neurological conditions .NSCs are also produced from Embryonic Stem Cells (ESCs), induced pluripotent Stem cells in vitro. Ethical problems, immunological problems and Tumorigenic problems makes obstacle during transplantation of these produced Exogenous NSCs. Some years back it was thought that Neurons Are Terminally differentiated Cells which can’t further differentiate, but recent Study shows NSCs in Sub ventricular zone (SVZ) have potential to produce glia and new neurons, here we discuss about use of endogenous NSCs in regeneration of damaged brain tissue. These Endogenous NSCs activate when there is traumatic insult to brain which in some cases Shows miraculous recovery.
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