PRP (platelet rich plasma) is new modality for management of Knee Osteoarthritis.According to published randomised clinical trials data, it shows that PRP will be definitely strong Alternative for Conventional management of Knee osteoarthritis. Intraarticular PRP injection shows better outcome in young, active, low grade osteoarthritis compare to hyaluronic acid. It need to be standardised protocol for PRP preparation, conduct high grade randomised clinical trials. Intraarticular PRP injection shows promising result after 3 months onwards, PRP treatment is Efficacious without encountering side effects.

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